Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage
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چکیده
منابع مشابه
Human Ex-Vivo Liver Model for Acetaminophen-induced Liver Damage
Reliable test systems to identify hepatotoxicity are essential to predict unexpected drug-related liver injury. Here we present a human ex-vivo liver model to investigate acetaminophen-induced liver injury. Human liver tissue was perfused over a 30 hour period with hourly sampling from the perfusate for measurement of general metabolism and clinical parameters. Liver function was assessed by cl...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep31916